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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5118a00cea88e10e20120bb8ee48a72262a4a34dd6c67af09348959e2cb06efd' 
  AND token = 'y76yRSJMJoitq0txAYq53G08sAnI9HS2teFrv5tDGZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}