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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd905ebb1835ab38d1188a755cb64240c3b3619270dee12f36385cbfb63c95775' 
  AND token = 'aTY59IoN/A3Q4Kxs13dLnTutKQ3Gz5ZHnNmPWjoauis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}