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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b566f3aa90bbd8e3cc601a0bb78344a4474369122c12bbe8c2dba226159e26f' 
  AND token = '86EdT+R8UtS/pI5NHWEW/Q1d2PrD41BQALUjG7ZiQEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}