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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cebf1c0b0ff42f44ef73875fb7db839125b398c41d7ad82b9303b3badeaafa4' 
  AND token = 'U+DuTKe1wpx86H+6lG2RYBqMBBn25wU+7716QwcmFWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}