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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f49c2b4c06138fb943159979df3b8609e129f8c53a1e56cefacfae07fa06be' 
  AND token = '78vGovQFRlizzDtq9s2E5RJlz0GD2wLsLCQhcvpn500=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}