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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461e2c16c7e1c082c4f206130774a99f1fb550fa11a6f0829cc2eec4571c5b41' 
  AND token = 'nzgNAXvOAUFThGvKE5xH6WLeG4ou77PEnlmXwvweenU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00120

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}