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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4f7b5feadff91470f64fc3a061eb9550b4e21bd9aca1072eaf4636b5a2ede0' 
  AND token = '1+wBhZHRPFB81gkeog1B1jEz0qVwFCtA4mQQ8R9xUEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}