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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba1bd48fd20a63508f3076b3d12ceee3a5cd105cf1201d7225a2b71cee3f6de' 
  AND token = 'CpW4Y83D/sQ7HmIpyySK2IBE/jFv1XWvf0qX1xbIKtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}