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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa35353201af55295b864571c564c57e8265799f23242fecfde0833558afbcdd' 
  AND token = 'NYi63pz1BDhBA6P2wtdwwwvzrkNExjSnHKXPTIffKBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}