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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45995fc27d76e8a61ac62c01161a2ffbf9b38a1f4558e20ffc3004151df836ea' 
  AND token = 'Ij2tRxMgXKOkMewqooSzmyMu5+8CUK9NcdCsKZ/Orgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}