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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22db94ab94bbfc9d213c98db7db4a40581afccb890a970b799bb3ce7b3be3eea' 
  AND token = '3HDnkcQ0pAvK45gM/B6cZD/EXHfYQ+CT9bpEjZYdkzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}