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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273766c3721807a9a5c077c27b93b6897709bd91d8a64221d028df1ce6a6df52' 
  AND token = 'U1HK7krWaxeMVi9j+gsTkbTOErrh/IXKDYxKLCzF1ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}