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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5279e1ffd40a33033a1a839679daf2bf8501c505b6cba3634e063230845d651f' 
  AND token = 'Lerr6TgxmPKVC6iWn9dRre029YqXx51Ruzpe7yGU+T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}