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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '334dded186870c3e8fea64345472897cb6e9ee202a3ca13d4902e834134148ed' 
  AND token = 'AvV5MqHzE6uDwF+z/3Vsk0Ql73NtPFmpJMNLx8uDYY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}