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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '116c7a02e769b72c82c7b41897d8144ba2ec29ffed2a38a0b48ada0fb6ce4f56' 
  AND token = 'TBUZ4NdpCUCzo/qAhyIRAWdrsXlnZBP3QddWiefiNSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}