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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '206fed125dd32b1408420343949cdaf35ea6dee7e65f3b3ce76c7dc5b9cc1543' 
  AND token = '/QW1Aap0rz8xFb0TDSaWR5lyX4xsEsaclXBAo79FZzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}