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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1bdc9c583d19ab3be42a76f180b2fd7ec7a25d81c4ef1df8707cd3646caf320' 
  AND token = 'AxZJbKwhDE1oYapTnKafdnxd/0zQwYuyjBqY1PxkR14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}