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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c745507c8dcaf8123e1718f629efc7122f177406d51950c9c7a6f28568baf1' 
  AND token = 'Y9qq0nVbEEp7UTn+fHaSy5giUIeGF7QSgPPo4SshaVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}