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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f535b66bd7aa000013046d4ce0e511578c2429becde5e4129f409d377ce52395' 
  AND token = 'Tw2Eq+emtUIwhFybrvuo8EtB5hmC3i/wG3XyOgG0KLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}