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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387c76d4058f18cb07c27746acb880c06636e499aa62181d2c63102988e29b41' 
  AND token = 'tXyw8jnPPpJFmtbGrhIuJ3H412wxX85/xyGClXun7Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}