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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05cb65b56a3f2c29eddf9c766a58116271b6c57a3f298b1dbd7d2a95f708fe8a' 
  AND token = 'WknZidtY1sYRohD/nmm068uNOH6ecfAsRrXyvsbAOCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}