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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1815e9789c51b5dbb206e3f5f086ecf90249919d8738b8ede28fe5a8d13695d' 
  AND token = '6uH/bc1TrxA3mYiX5TwMGgR/ysEbrx7PGoAY0JcQa0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}