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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d8e841571b8d158148352ab59e26823bf80ca7b7ebf52e6305e402854710d6' 
  AND token = 'DnlacF9GIzdaNweGwWadq0OIm+6JNb4UIID/Gom0YDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}