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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6ca1b9aaf7d24fc93c478cab097e2c9f1da6df62b201c1e3f2be3a7920361b3' 
  AND token = 'sFk+amSIifZpFa38ynFVR+AdZh4+c9AQvN+3OvmWTe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}