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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cdc2e745149ec36f49416b471a86d72e8dd90cb90f6d186890958979d6314f' 
  AND token = 'L/je/BZqMCN/bBQasiwbJohTWl6mfE8/zT5gqTs0ybg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}