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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65728d69ebcbf8ff6f1dbe7de871fcbf5760f682705b001451feff71d93b4f70' 
  AND token = 'DdjTzElSoneH/tIamjRVTp+SGzhuPugx8zh2S6Tf8lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}