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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5111be2e1fb2ee1f39d306977f2df03f68a7264d616c2376078f8ca89107a7d' 
  AND token = 'avxk8MnU4vN8kZvqqcjVJOo4ww3PajL6FUpLEIuo+Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}