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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258d8662f351745421642cafc4c00f6eab2a760c0954db9bcb011cdd22b59049' 
  AND token = 'Qafu17ee2ZW85ohHVw0t4YQF/1DDGvIyWApBsMRAmyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}