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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28188adc9ab1674c7c19fa17bb7a592f607e54ddf73c5d792af80239fa693a5a' 
  AND token = 'LnuOJ2WHNn4UtfphZVxk6jNJZcykDUHE2w7X9ZpBCWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}