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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2be7aa43eeef2ff8cc7e8b81ed4a6801823fb36784aac0baa0300ca67cb64f' 
  AND token = 'gJsNx+yEz6GOt345beOYOYwAS6YZ/T8bbYMCfZfI8bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}