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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dad01069034625a8a1c4bc7d6c6106083dcb9f66e10d9e839ad81333211b732' 
  AND token = '3blG9L+ZV7px0sEoj1UAhkqrl46CSm6FUDGZVTjjzz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}