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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef46cc888fd927cca0fc933b8446e1fafa880dd907f2cfed19cd4f4878708a9' 
  AND token = '7sFF3O8n4SSFlv//DHCGa3u1SXEjMMWTc2eaOVH7LvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}