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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a914c9359ab65f3403378dcc8213fb0527ca2b967d0a0b24fbfbaf3b5023f253' 
  AND token = 'FZi4dn/RRFO800LuIX1cXYLLcb0v1rXwQrcqxNGS/tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}