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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51291e459a5c04d1de64fd7afd3b9faa6908c6ae388b8a2c1617e87aa5e0e37e' 
  AND token = 'uMsExRXL0q2C4D6pzS2DbUMSu4G9+B3qHx5mQBFf6nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}