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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4336c5573a0762c83fdfda85102d60b6243812a58b1397bb592a18dd9af537f' 
  AND token = 'fZP67HLGOf+EvctIot+zYTbuHp18Vz2tLdSzRiR1oQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}