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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4485977c7fac0b6d8bf95495e39c6fc66538a80ea632256db1b3a3d58374d23d' 
  AND token = 'W9v3YWW2h+uEnwU6pp+8GHU7DMupb5XYsR+ulA56qlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}