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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7edd98e4ee1549479a8f1a8423e7319f50bb63fb8fa33697bd9e807a31d231' 
  AND token = '2MRsX3SP1N086i3EAmfdMFqShZNUcj1OislJWK6TkhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}