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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77de8173a9aa476982c6849c55931c324546e08e930098426494616476a1349c' 
  AND token = '6UFqd/ZHTKcL/LiIjVB0VLo0mkeVVXkO5vnCW95uW4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}