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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8431d6849647bd8446a02e95abbd1045000eb529c3c35bce7ccf8ed3b8ffc41' 
  AND token = 'WQZtozkuxAeTZoWkyOWFEgHalsnpPvrfw/F4cuS21as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}