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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738c848074cdd472f7e44367f814da9702d6946139aa2d7339b7eaa430061b2b' 
  AND token = '+6BI67FRC6fOCJScfqgpq3KpA0PCdeVtHhHiyczvxgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}