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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da32802fbc383922144b8e6881749bc72f360f9305c06c98021a2f795e2eede4' 
  AND token = 'p+pdm8kDFbL5DT6iImsTgWcok8tKHe96eK29wrgz2r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}