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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c478a2802db12a1a4e0eb039e4b4af492eb48fcde10ed3e9d746cee6d129fd08' 
  AND token = 'b8vekXn/5aAmx+7U0bimTDv0x+6Y1j0odtHa9LH+rgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}