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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35f7b1b835e3624a05b9f8ad22d273d74f9e50bfdd2712734f5cbc05e87a91c9' 
  AND token = 'Lkglqw1AdG/sb0LB1pstxrZzPn5gIAddAOyxaM0ey7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}