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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b24341d2c854e1ee935bb9d00c984e08c2cb4d75affa265f54f20a08aea32ab' 
  AND token = 'Nk5vBcarvT8nWS4vzZfOqDR3CfNGoUN/e8KhW1N1XUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}