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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0a4b9c50daf2a08bcb09bcd10edb070c08720faa3a44c234988b56e873e60c' 
  AND token = 'p0UTUFVDh3vi5ST9slV2oBxMrVmbXAYi4bfKFrwvSk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}