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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292dc1e0da95d3ac6b16c9c75748187f99daf73fd8795b0fc7023b0326be1021' 
  AND token = 'ADF01hDoyMrkV9yCnp2t0epFBL1RXSe2EzNlwA6FtPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}