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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4019756ca765e5602df23dabb7f53f4887e4a537f7d35d47c40d0a1277c209a1' 
  AND token = 'fbprx7U5uLC7wi8/gf7/+E9ZAbVgCa1XoG2DP0fBrBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}