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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dbb081e4a3a3f5065b5784bd9491c893b64da7b52b41a5c2f00524fe8f65501' 
  AND token = 'U/4uKYv6XYDSmDK/U35movvIVDZ+fNj29t4F0/AEsj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}