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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aa8f2198506d111e778853e3f3d963a89c0712aa0e82025c99d4fa0ec81e469' 
  AND token = '5bKrlzWTT6T2uW5FW3I5OxlUiLAU4rvPQWG3WXUFV4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}