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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4ec77cf48d6889f3771916f681a582d18f771913db8e3c8cb4d0f2478148ebe' 
  AND token = 'ZPX8tsgMmxHQ8UpnHoxfm9PI1lewYyLAVOjJrz0wVpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}